If you miss a dose, take it as soon as you remember. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. This is called a medicine interaction. Does isosorbide mononitrate (Monoket) affect your kidneys? Do not drive, use machinery, or do anything that needs alertness until you can do it safely. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. In: Textbook of Natural Medicine. This document does not contain all possible drug interactions. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Disclaimer. Cardizem may also be used for purposes not listed in this medication guide. . Isosorbide mononitrate belongs to the group of medicines called nitrates. Even if the medication is working, you may experience some unwanted side effects. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Each day, take the first dose when you wake up, then take the second dose 7 hours later. The most common side-effect is headache. Glyceryl trinitrate (GTN) is commonly prescribed for this. This is called a medicine interaction. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Before MeSH Select a condition to view a list of medication options. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Yet many herbal supplements may interact with heart disease medicines. Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. Do not let anyone else take your medication. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Try to keep your regular appointments with your doctor. Aspirin has an average rating of Isosorbide tablets are also used with other medications to treat heart failure. Do not take a double dose to make up for a missed one. https://naturalmedicines.therapeuticresearch.com. We comply with the HONcode standard for trustworthy health information. If we combine this information with your protected The tablet usually is taken two or three times daily. Integrative medicine (complementary and alternative medicine). Herbal medications in cardiovascular medicine. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). In: Current Medical Diagnosis & Treatment 2022. . This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. Try our Symptom Checker Got any other symptoms? Registered in England and Wales. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). It does not work fast enough to relieve the pain of an angina attack that has already started. Canada residents can call a provincial poison control center. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. National Library of Medicine The https:// ensures that you are connecting to the Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Nitrates in the management of acute coronary syndrome. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. I would rather take the chance of a heart attack than have no quality of life. No you may not. 1998 Oct;61(10):577-83. What conditions does Isosorbide Mononitrate treat? As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. The two dosage regimens were equally efficient for the relief of angina pectoris without development of tolerance. May also be prescribed off label for Esophageal Spasm. This should pass after a few days. Would you like email updates of new search results? Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). To view a report comparing 3 (or more) medications, please sign in or create an account. Journal of the American College of Cardiology. The extended-release capsule usually is taken once daily. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Using this medicine with any of the following medicines is not recommended. It might help to take isosorbide mononitrate and dinitrate after meals. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. B12 and folic acid is essential along with iron. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Limit alcoholic beverages. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Compare a few possible alternatives below. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Ask your doctor before using aspirin together with alcohol. 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Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Advertising revenue supports our not-for-profit mission. Isosorbide mononitrate | Drugs | BNF | NICE Evening primrose. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Duplication for commercial use must be authorized by ASHP. Always consult your healthcare provider. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Tolerance is more likely to happen if you don't take your dose at the same time every day. All rights reserved. Saper RB. Continue to take isosorbide even if you feel well. the unsubscribe link in the e-mail. If tolerance is suspected during the use of transdermal patches they should be left off for 8-12 hours (usually overnight) in each 24 hours; in the case of modified-release tablets of isosorbide dinitrate (and . Conclusions: Discuss the risks and benefits with your doctor. information highlighted below and resubmit the form. 5.0 out of 10 from a total of Is not subject to the Controlled Substances Act. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Please note that only the generic name of each medication is listed below. Consult your doctor before breast-feeding. If headaches continue or become severe, tell your doctor promptly. What should I know about storage and disposal of this medication? Many common herbal supplements interact with common heart medicines. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Upgrade to Patient Pro Medical Professional? Liperoti R, et al. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Coenzyme Q-10 Natural Medicines. Accessed Sept. 7, 2022. Isosorbide mononitrate Alternatives Compared - Drugs.com Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. Consult your pharmacist or local waste disposal company. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Talk to your doctor if you are using marijuana (cannabis). Nitrates | Prescribing information | Angina | CKS | NICE information submitted for this request. AHFS Patient Medication Information. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. It will not treat an angina attack that has already begun. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied.