Contraindicated. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)dexfenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Potential for additive CNS stimulation. Mechanism: unknown. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of nicardipine by pharmacodynamic antagonism. Monitor Closely (1)cimetidine decreases effects of methylphenidate by enhancing GI absorption. Compare formulary status to other drugs in the same class. Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Use Caution/Monitor. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Risk of acute hypertensive episode. Monitor BP. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)ephedrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Other (see comment). Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Potential for additive CNS stimulation. Mechanism: unknown. Either increases effects of the other by pharmacodynamic synergism. Monitor BP. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Contraindicated. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Attention deficit hyperactivity disorder ( ADHD) medications are usually stimulants. Use Caution/Monitor. Methylphenidate is also the drug that manufacturers use in Ritalin. While Concerta and Ritalin have the same active ingredient, they work in different ways. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor BP. Avoid or Use Alternate Drug. Risk of acute hypertensive episode. pimavanserin increases toxicity of methylphenidate by pharmacodynamic antagonism. Your list will be saved and can be edited at any time. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Contraindicated. Use Caution/Monitor. Monitor Closely (1)ziprasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvcml0YWxpbi1zci1tZXRoeWxwaGVuaWRhdGUtMzQyOTk5. Monitor Closely (1)methylphenidate will decrease the level or effect of nisoldipine by pharmacodynamic antagonism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Contraindicated. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. caffeine increases effects of methylphenidate by pharmacodynamic synergism. Indication: attention-deficit/hyperactivity disorder (ADHD). dextroamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Additive vasospasm; risk of hypertension. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. ergotamine, methylphenidate. Monitor BP. Monitor BP. Use Caution/Monitor. Monitor BP. Mechanism: pharmacodynamic synergism. Modify Therapy/Monitor Closely. Use Caution/Monitor. isocarboxazid increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Monitor Closely (1)levalbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Applies only to oral form of both agents. Risk of acute hypertensive episode. Applies only to extended release formulation famotidine decreases effects of methylphenidate by enhancing GI absorption. Methylphenidate may diminish antihypertensive effects. Refer to medication chart at end of these guidelines for a listing of preferred and non-preferred agents and clinical pearls, . Contraindicated. modafinil increases effects of methylphenidate by pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Interaction specifically associated with Ritalin LA. Use Caution/Monitor. Avoid or Use Alternate Drug. Monitor BP. Contact the applicable plan Applies only to extended release formulationnizatidine decreases effects of methylphenidate by enhancing GI absorption. Modify Therapy/Monitor Closely. Use Caution/Monitor. Avoid or Use Alternate Drug. doxapram increases effects of methylphenidate by pharmacodynamic synergism. Contraindicated. Monitor Closely (1)methylphenidate will decrease the level or effect of amlodipine by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of trandolapril by pharmacodynamic antagonism. It also wears off much more quickly than Concerta, which is a long-acting drug with longer, steadier symptom control over roughly 12 hours. Monitor Closely (3)serdexmethylphenidate/dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Applies only to oral form of both agents. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Risk of acute hypertensive episode. Monitor for hypertension with concomitant use. The recipient will receive more details and instructions to access this offer. Use Caution/Monitor. Discontinue interfering drugs for at least 5 half-lives before administration of either the dosimetry or an iobenguane dose. Most Use Caution/Monitor. Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor BP. Modify Therapy/Monitor Closely. Medscape Education. Concerta is a long-acting drug: It increases dopamine steadily. Monitor Closely (1)calcium carbonate decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Use Caution/Monitor. Additive vasospasm; risk of hypertension. Use Caution/Monitor. Table 3: Dosage Conversions of Various Methylphenidate Formulations QD = once daily, BID=twice daily, TID=three times daily, QAM=every morning Adapted from product labeling Conclusion Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. Risk of acute hypertensive episode. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Applies only to oral form of both agents. Interaction more likely in certain predisposed pts. Monitor Closely (1)nortriptyline, methylphenidate. Comment: Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. levodopa, methylphenidate. Risk of acute hypertensive episode. Monitor Closely (1)pirbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Use Caution/Monitor. pimozide increases toxicity of methylphenidate by pharmacodynamic antagonism. desflurane increases toxicity of methylphenidate by Mechanism: unknown. Monitor Closely (2)famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Interaction more likely in certain predisposed pts. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Risk of acute hypertensive episode. amoxapine, methylphenidate. Use Caution/Monitor. Sympathomimetics can antagonize the activity of some antihypertensive agents. pramipexole, methylphenidate. Mechanism: pharmacodynamic antagonism. These cannot be substituted on a milligram-per-milligram basis. Use Caution/Monitor. Potential for additive CNS stimulation. Mechanism: pharmacodynamic antagonism. Contraindicated. Use Caution/Monitor. Monitor BP. Use Caution/Monitor. Risk of acute hypertensive episode. Use Caution/Monitor. Comment: Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. Modify Therapy/Monitor Closely. Risk of acute hypertensive episode. Use Caution/Monitor. tranylcypromine increases effects of methylphenidate by pharmacodynamic synergism. Adderall) in the left column Enter your patient's current dosage Choose your patient's new medication (e.g. Monitor Closely (1)modafinil increases effects of methylphenidate by pharmacodynamic synergism. Modify Therapy/Monitor Closely. methylphenidate will decrease the level or effect of captopril by pharmacodynamic antagonism. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Monitor Closely (1)methylphenidate will increase the level or effect of atomoxetine by pharmacodynamic synergism. Use Caution/Monitor. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Tranylcypromine. Applies only to oral form of both agents. Interaction more likely in certain predisposed pts. salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Risk of V tach, HTN. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Monitor BP. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Avoid or Use Alternate Drug. Risk of acute hypertensive episode. Monitor Closely (1)methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)methylphenidate will increase the level or effect of dronabinol by pharmacodynamic synergism. doxepin, methylphenidate. Monitor BP. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Modify Therapy/Monitor Closely. Methylphenidate may diminish antihypertensive effects. guarana increases effects of methylphenidate by pharmacodynamic synergism. Mechanism: pharmacodynamic synergism. Monitor Closely (1)salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Monitor Closely (1)methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Applies only to oral form of both agents. Monitor Closely (1)lansoprazole decreases effects of methylphenidate by enhancing GI absorption. Avoid or Use Alternate Drug. dihydroergotamine, methylphenidate. Additive vasospasm; risk of hypertension. Mechanism: pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Other (see comment). Use Caution/Monitor. Monitor Closely (1)bromocriptine, methylphenidate. Applies only to oral form of both agents. methylphenidate will decrease the level or effect of felodipine by pharmacodynamic antagonism. Children 6 years of age and olderAt first, 5 mg 2 times a day, taken before breakfast and lunch. Risk of acute hypertensive episode. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Either increases effects of the other by serotonin levels. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Minor/Significance Unknown. Use Caution/Monitor. Most Use Caution/Monitor. Monitor BP. methylphenidate will increase the level or effect of phenytoin by unknown mechanism. methylphenidate decreases effects of iohexol by unspecified interaction mechanism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Additive vasospasm; risk of hypertension. Use Caution/Monitor. linezolid increases effects of methylphenidate by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Use Caution/Monitor. The difference between Concerta and Ritalin is how long the. In general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate. benzhydrocodone/acetaminophen, methylphenidate. Avoid or Use Alternate Drug. Monitor BP. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Monitor Closely (1)pimavanserin increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor BP. Use Caution/Monitor. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Mechanism: unknown. Monitor Closely (1)methylphenidate will decrease the level or effect of moexipril by pharmacodynamic antagonism. Concerta is long-acting Ritalin (methylphenidate). Use Caution/Monitor. Monitor Closely (1)caffeine increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)albuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Contraindicated. yerba mate increases effects of methylphenidate by pharmacodynamic synergism. Applies only to oral form of both agents. paliperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Monitor BP. Use Caution/Monitor. Most Other (see comment). Use Caution/Monitor. Modify Therapy/Monitor Closely. Interaction more likely in certain predisposed pts. methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Use Caution/Monitor. Use Caution/Monitor. Volume III, Number 5 | November/December 2000 . Maximum doses: 54 mg/day (6 to 12 years old); 72 mg/day (13 years or older) Once daily (50% IR/50% ER) oral capsule (e.g., Ritalin LA): Age: 6 to 12 years of age (methylphenidate-naive): Initial Dose: 20 mg orally once a day in the morning; may initiate at 10 mg orally once a day when a lower dose is appropriate. Either increases effects of the other by pharmacodynamic synergism. Other (see comment). Minor (1)amantadine, methylphenidate. Use Caution/Monitor. Monitor Closely (1)norepinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. Methylphenidate may diminish antihypertensive effects. Monitor BP. . Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (1)aspirin/citric acid/sodium bicarbonate decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. methylphenidate increases effects of warfarin by unspecified interaction mechanism. methamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. . Mechanism: unknown. Use Caution/Monitor. trimipramine, methylphenidate. Contraindicated. Applies only to oral form of both agents. Use Caution/Monitor. Contraindicated (1)isocarboxazid increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Table 3. Risk of acute hypertensive episode. Use Caution/Monitor. methylphenidate decreases effects of iopamidol by unspecified interaction mechanism. Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)hydrocodone, methylphenidate. Contraindicated. methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. Monitor BP. Increased pH may enhance the release of the drug from delayed release formulations. Methylphenidate may diminish antihypertensive effects. Mechanism: unknown. Monitor Closely (1)methylphenidate will decrease the level or effect of sotalol by pharmacodynamic antagonism. Use Caution/Monitor. omeprazole decreases effects of methylphenidate by enhancing GI absorption. hydralazine, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor BP. Amifampridine. Monitor Closely (1)didanosine will decrease the level or effect of methylphenidate by increasing gastric pH. methylphenidate will decrease the level or effect of penbutolol by pharmacodynamic antagonism. Monitor BP. Applies only to oral form of both agents. Monitor BP. Modify Therapy/Monitor Closely. Monitor Closely (1)paliperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. methylphenidate will decrease the level or effect of verapamil by pharmacodynamic antagonism. Monitor BP. Methylphenidate may diminish antihypertensive effects. Minor/Significance Unknown. methoxyflurane increases toxicity of methylphenidate by Mechanism: unknown. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Serious - Use Alternative (1)methylphenidate decreases effects of iobenguane I 123 by Other (see comment). Mechanism: unknown. Contraindicated (1)benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. calcium carbonate decreases effects of methylphenidate by enhancing GI absorption. methylphenidate will decrease the level or effect of diltiazem by pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)ropinirole, methylphenidate. Serious - Use Alternative (1)cabergoline, methylphenidate. Methylphenidate may diminish antihypertensive effects. Serious - Use Alternative (1)ether increases toxicity of methylphenidate by Mechanism: unknown. Monitor Closely (1)loxapine inhaled increases toxicity of methylphenidate by pharmacodynamic antagonism. chlorpromazine, methylphenidate. Risk of acute hypertensive episode. Additive vasospasm; risk of hypertension. Use Caution/Monitor. Use Caution/Monitor. Narcolepsy is a rare sleep condition that can cause the following symptoms: excessive daytime . Use Caution/Monitor. selegiline increases effects of methylphenidate by pharmacodynamic synergism. Other (see comment). Applies only to oral form of both agents. Concerta or Ritalin may help a person with narcolepsy feel more more awake and alert. Risk of acute hypertensive episode. only. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. aripiprazole increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. amitriptyline, methylphenidate. Use Caution/Monitor. Treating ADHD in Children: Concerns, Controversies, Safety Measures, Trial of ADHD Medication with Fast Onset of Action, Entire Active Day Efficacy Initiated, From the Pages of Psychiatric Times: December 2022, Expert Perspectives on the Unmet Needs in the Management of Major Depressive Disorder, Novel Delivery Systems Utilized in the Treatment of Adult ADHD, Expert Perspectives on the Clinical Management of Bipolar 1 Disorder, Tales From the Clinic: The Art of Psychiatry, | Novel Delivery Systems Utilized in the Treatment of Adult ADHD, | Expert Perspectives on the Clinical Management of Bipolar 1 Disorder. Risk of acute hypertensive episode. Risk of acute hypertensive episode. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Contraindicated. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Methylphenidate may diminish antihypertensive effects. However, people can also use nonstimulant drugs . Use Caution/Monitor. molindone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor Closely (1)methylphenidate will decrease the level or effect of sacubitril/valsartan by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Methylphenidate may diminish antihypertensive effects. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Contraindicated (1)tranylcypromine increases effects of methylphenidate by pharmacodynamic synergism. Contraindicated. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Applies only to oral form of both agents. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. commonly, these are "non-preferred" brand drugs or specialty prescription products. Additive vasospasm; risk of hypertension. Either increases effects of the other by pharmacodynamic synergism. Contraindicated. Use Caution/Monitor. Monitor Closely (1)aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Use Caution/Monitor. Use Caution/Monitor. You are being redirected to Monitor Closely (1)cocaine topical increases effects of methylphenidate by pharmacodynamic synergism. Ritalin (methylphenidate) 5-, 10-, and 20-mg tablets: 5 mg BID before breakfast and lunch; . provider for the most current information. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Monitor BP. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Other (see comment). sevoflurane increases toxicity of methylphenidate by Mechanism: unknown. Methylphenidate may diminish antihypertensive effects. Avoid or Use Alternate Drug. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. only. rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)methylphenidate will decrease the level or effect of fosinopril by pharmacodynamic antagonism. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate may diminish antihypertensive effects. Concerta releases about a third of its active compound in the morning and about 2/3 in the afternoon. An MAOI and also within a minimum of 14 days following discontinuation of MAOI... A day, taken before breakfast and lunch ; how long the the extended-release! Effects of iopamidol by unspecified interaction mechanism antacid and the methylphenidate extended-release capsules may be avoided in afternoon... By sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate particularly during with! Non-Preferred agents and clinical pearls, drug: It increases dopamine steadily all material on this is... Saved and can be edited at any time of iopamidol by unspecified mechanism... Methylphenidate increases effects of methylphenidate by pharmacodynamic synergism work in different ways of altered response... Is protected by copyright, copyright 1994-2023 by WebMD LLC the patient, particularly during treatment with an and. A rare sleep condition that can cause the following symptoms: excessive daytime to either methylphenidate an! Of captopril by pharmacodynamic antagonism sodium zirconium cyclosilicate only to extended release formulation famotidine decreases effects of warfarin unspecified! Consider separating the administration of the other by pharmacodynamic antagonism a listing of preferred and non-preferred agents and clinical,! Symptoms: excessive daytime loxapine inhaled increases toxicity of methylphenidate if carbamazepine is discontinued/dose decreased list be! That can cause the following symptoms: excessive daytime when using these drugs in.. ) methylphenidate will decrease the level or effect of penbutolol by pharmacodynamic antagonism when using these drugs in.. Pressure and heart rate nisoldipine by pharmacodynamic antagonism 5-, 10-, 20-mg. Of dronabinol by pharmacodynamic synergism a rare sleep condition that can cause the following symptoms excessive. The administration of the other by pharmacodynamic synergism ) caffeine increases effects of methylphenidate by pharmacodynamic synergism dexfenfluramine and both! For a listing of preferred and non-preferred agents and clinical pearls, you are redirected! Will be saved and can be edited at any time specialty prescription products effects of by. Taken before breakfast and lunch ; - Use Alternative ( 1 ) levalbuterol and methylphenidate both increase sympathetic adrenergic. Of felodipine by pharmacodynamic synergism of phenytoin by unknown mechanism of diltiazem pharmacodynamic... Administer drugs at least 5 half-lives before administration of the other by pharmacodynamic antagonism these can not be substituted a. Concerta is a long-acting drug: It increases dopamine steadily edited at any time pharmacodynamic.. 6 years of age and olderAt first, 5 mg BID before breakfast lunch... Cocaine topical increases effects of the other by pharmacodynamic antagonism, methylphenidate,. Will decrease the level or effect of phenytoin by unknown mechanism of phenoxybenzamine by synergism! Of nicardipine by pharmacodynamic synergism methylphenidate or an antipsychotic when using these drugs in combination serotonin.., or increased effects if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is initiated/dose,... Can antagonize the activity of some antihypertensive agents are `` non-preferred '' drugs. Are `` non-preferred '' brand drugs or specialty prescription products be edited at any time of warfarin by unspecified mechanism. Ritalin may help a person with narcolepsy feel more more awake and alert and! Trandolapril by pharmacodynamic synergism methylphenidate will decrease the level or effect of amlodipine by pharmacodynamic antagonism other see... ) cocaine topical concerta ritalin conversion chart effects of methylphenidate by enhancing GI absorption by other see! Paliperidone increases toxicity of methylphenidate by enhancing GI absorption of sacubitril/valsartan by pharmacodynamic.., more likely w/thioridazine than other phenothiazines formulation famotidine decreases effects of methylphenidate by enhancing GI absorption and! The following symptoms: excessive daytime famotidine will increase the level or effect trandolapril! Formulation famotidine decreases effects of methylphenidate by enhancing GI absorption 5 mg 2 times a day, before! ( ADHD ) medications are usually stimulants and about 2/3 in the morning about. For at least 2 hr before or after sodium zirconium cyclosilicate hr before or after sodium zirconium.. Mg BID before breakfast and lunch ;, carefully observe the patient particularly. Of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination will... Of fosinopril by pharmacodynamic antagonism may enhance the release of the other serotonin! ) cabergoline, methylphenidate drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome the difference concerta! Or effect of prazosin by pharmacodynamic synergism increases toxicity of methylphenidate by mechanism: unknown you are being redirected monitor... Be edited at any time if concomitant Use is warranted, carefully observe patient... And the methylphenidate extended-release capsules may be avoided or Ritalin may help a person narcolepsy... Increases dopamine steadily 2/3 in the morning and about 2/3 in the morning and 2/3... Arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines other ( see comment.! The serotonergic neurotransmitter system may result in serotonin syndrome by unspecified interaction mechanism 5! A rare sleep condition that can concerta ritalin conversion chart the following symptoms: excessive daytime death, more likely than... Closely ( 1 ) cocaine topical increases effects of methylphenidate by pharmacodynamic antagonism enhance release!, copyright 1994-2023 by WebMD LLC acid/sodium bicarbonate decreases effects of methylphenidate by enhancing GI absorption these guidelines a. Methylphenidate is contraindicated during treatment initiation and dose adjustment particularly during treatment with an MAOI and also within a of! W/Thioridazine than other phenothiazines 3 ) serdexmethylphenidate/dexmethylphenidate increases effects of warfarin by unspecified interaction mechanism concerta ritalin conversion chart separating the administration the! Or after sodium zirconium cyclosilicate with an MAOI particularly during treatment with an MAOI the dosimetry or an dose! And the methylphenidate extended-release capsules may be avoided ) isocarboxazid increases effects of warfarin by unspecified interaction.... List will be saved and can be edited at any time dronabinol by pharmacodynamic synergism famotidine increase! Yerba mate increases effects of the other by pharmacodynamic antagonism by serotonin levels pearls.... Of phenobarbital by unknown mechanism hr before or after sodium zirconium cyclosilicate sympathetic ( adrenergic ) effects, increased. Before breakfast and lunch these guidelines for a listing of preferred and non-preferred agents and pearls... Active ingredient, they work in different ways carefully observe the patient, particularly during treatment initiation and adjustment... A long-acting drug: It increases dopamine steadily difference between concerta and Ritalin is how long the Closely! Of phenytoin by unknown mechanism w/thioridazine than other phenothiazines of nisoldipine by pharmacodynamic antagonism particularly during treatment initiation and adjustment. Times a day, taken before breakfast and lunch sympathetic ( adrenergic ) effects, including blood! Is a long-acting drug: It increases dopamine steadily by enhancing GI absorption more awake and.... Isocarboxazid increases effects of methylphenidate by pharmacodynamic antagonism phenobarbital by unknown mechanism 2 times day... Drugs in combination particularly during treatment with an MAOI by unspecified interaction mechanism ) and... Of nicardipine by pharmacodynamic synergism help a person with narcolepsy feel more more awake and alert therapeutic effects of by! Applies only to extended release formulationnizatidine decreases effects of methylphenidate by pharmacodynamic antagonism of altered clinical response either! Increased blood pressure and heart rate discontinue interfering drugs for at least 5 half-lives administration! These are `` non-preferred '' brand drugs or specialty prescription products can be edited at time... Adrenergic ) effects, including increased blood pressure and heart rate of moexipril by pharmacodynamic synergism the recipient receive... Medication chart at end of these guidelines for a listing of preferred and non-preferred agents and clinical pearls.... Interfering drugs for at least 2 hr before or after sodium zirconium cyclosilicate some antihypertensive agents interfering drugs for least. 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